The ANA Screen measures antibodies in your blood produced when your body’s immune system mistakenly attacks healthy cells and tissues. This test can help your healthcare provider diagnose autoimmune diseases.

Test Purpose: • Screen for potential autoimmune diseases • Detect antibodies attacking healthy cells • Initial diagnostic tool for systemic autoimmune conditions

Clinical Significance Potential Conditions Detected: • Systemic Lupus Erythematosus (SLE) • Rheumatoid Arthritis • Scleroderma • Sjögren’s Syndrome • Addison Disease • Autoimmune Hepatitis

Important Testing Considerations Interpretation Guidelines: • Positive result does NOT confirm autoimmune disease • 20% of healthy adults can have positive ANA • Only 11-13% of positive ANA tests indicate lupus

Requires comprehensive clinical evaluation. A positive ANA screen is just the first step in diagnosing potential autoimmune conditions, requiring further specialized testing and clinical assessment.