The Lp-PLA2 Activity test is a blood test that measures the activity of an enzyme called Lp-PLA2. This test can help predict your risk of developing coronary heart disease.
Key Purpose:
- Assess cardiovascular disease risk
- Identify hidden heart disease potential
- Evaluate inflammation in blood vessels
Role in the Body Critical Functions:
- Measure enzyme activity in lipoproteins
- Indicate potential plaque vulnerability
- Support understanding of heart disease risk
- Help predict potential cardiovascular events
Normal/Optimal Ranges Lp-PLA2 Activity Levels:
- Optimal: 0-224 nmol/min/mL
- Low Risk: < 225 nmol/min/mL
- High Risk: ≥ 225 nmol/min/mL
Test Limitations Potential Constraints: • Not a definitive heart disease diagnosis • Limited predictive accuracy • Requires additional testing for confirmation • Sensitivity varies across populations • Effectiveness differs by sex and race Low
Results May Indicate Potential Conditions:
- Lower cardiovascular risk
- Less inflammatory activity
- Healthier blood vessel condition
High Results May Suggest Potential Conditions:
- Increased heart attack risk
- Higher cardiovascular inflammation
- More vulnerable arterial plaque
- Potential need for further cardiovascular screening
Always require professional medical interpretation for accurate diagnosis.


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