This lab test measures thyroid peroxidase (TPO) and thyroglobulin antibodies in your blood. It can help diagnose autoimmune thyroid conditions.

Thyroid Antibodies are autoantibodies that target different components of the thyroid gland, serving as critical diagnostic markers for autoimmune thyroid disorders.

Key Types of Thyroid Antibodies: • Anti-Thyroid Peroxidase (TPOAb) • Anti-Thyroglobulin (TgAb) • Thyroid Stimulating Hormone Receptor Antibodies (TRAb)

Clinical Significance:
Helps diagnose and monitor: • Hashimoto’s thyroiditis • Graves’ disease • Potential thyroid dysfunction

Diagnostic Insights: • TPOAb prevalence: • 90% in Hashimoto’s disease • 70% in Graves’ disease • 10% in individuals with normal thyroid function • TgAb prevalence: • 60-85% in Hashimoto’s disease • 30-60% in Graves’ disease • 25% in thyroid cancer patients

Important Considerations: • Can develop years before clinical diagnosis • Indicate increased risk of future thyroid disorders • Often associated with other autoimmune conditions

Thyroid antibody tests provide healthcare providers with a sophisticated tool for assessing thyroid autoimmune activity and potential hormonal imbalances.